＃203 Wet-lab Senior Scientist

※This job is only for residents of Japan.

Company Overview

This company is a biotech founded in 2021. They are developing a novel genome-editing technology that is independent of the CRISPR/Cas system, with the goal of enabling innovative therapeutic strategies. With this technology, they aim to overcome limitations and address challenges associated with conventional genome editing.
They are advancing our platform technology while conducting translational research to apply it to disease therapeutics.

Job Description

•Execute drug discovery programs using proprietary genome-editing technology.
└ Advance CAR-T cell therapy programs.
└ Advance gene replacement therapy programs.
• Conduct functional evaluation of genome-edited cells in vitro and ex vivo.
• Evaluate genome-editing effects in vivo using mouse models.
• Design and evaluate gene therapy vectors (non-viral and AAV systems).
• Design and optimize gene expression control systems for human therapeutic applications, including the design and evaluation of regulatory elements and tissue- and cell-type-specific expression.
• Lead and execute projects with external research collaborators.
Note: Responsibilities listed here cover the scope for multiple open positions. Individual scope will be
assigned based on experience and organizational needs.

Requirements

• Ph.D. degree or equivalent experience.
• Strong research background in molecular biology, cell biology, or molecular pharmacology.
• Ability to independently design research tasks and execute hypothesis-driven experiments.
• Strong communication skills across internal and external teams.

• Sufficient knowledge and research experience in the field of immunology (experience in CAR-T cell therapy research is a plus)

• Experience in in vivo (mouse) evaluation

Preferred Requirements

• Substantial knowledge and research experience in immunology.
• Substantial experience with animal experiments using mice.
• Knowledge of, or hands-on experience in, therapeutic development for human diseases.
• Hands-on experience in gene expression control or gene therapy research using human cells.
• Demonstrated research achievements such as high-quality publications and/or patents.

Terms and Conditions

• Annual Salary: 5 – 10 million JPY

• Employment type: Fixed-term employment (can be changed to permanent employment after one year if both parties agree)

• Bonus: None

• Salary Increase: Once a year

• Probation Period: 3 months

• Location: Kanagawa

• Social Insurance: Fully covered

• Working Hours: Based on 9:00-18:00 (left to the individual’s discretion)

• Holidays: Saturdays, Sundays, and National Holidays

• Average Overtime: Discretionary labor system

• Smoking Cessation Measures: Non-smoking indoors

Selection Process

• Selection Flow: Interview 2 (The final interview is an in-person interview)

• Required Documents: They require a resume and a curriculum vitae (CV) for the initial screening.

• Interview Language: Their interviews can be conducted in either Japanese or English.